Gepabene - instructions for use. Gepabene - instructions for the use of tablets, indications, composition, side effects, analogues and price

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Often, people who drink, especially those who are prone to prolonged binges or suffering from chronic alcoholism, experience tingling and pain in the right side under the ribs. Often chalked up to poor nutrition or low fluid intake, however, these signals can have far-reaching and unpleasant consequences. This is how the liver can react to the negative effects caused by alcohol consumption or frequent drug use. On the recommendation of doctors, and most often trusting in advertising, many people begin to use various medications to restore the functioning of the liver, while not giving up their addiction to alcoholic beverages and absolutely not thinking about what will happen from such an interaction. One of these drugs is Gepabene. What kind of medicine is this and what are the consequences of its compatibility with alcohol.

Causes of liver dysfunction in alcohol dependent people

Everyone knows that the liver is responsible for the fight against dangerous toxins and poisons in the body. It is she who helps the drinking person deal with the toxic decomposition products of ethanol. And if there are a large number of them due to prolonged binges, then this body will have to work almost to the point of wear and tear.

In addition, people who abuse alcohol are unlikely to have a balanced diet or quality food in their diet. Almost always, this is what comes to hand: fast food, fatty and cold food, which is slowly processed and absorbed by the body for a long time. Such products often contain chemical preservatives and dyes, which also have a detrimental effect on the liver, increasing the load on this vital organ.

This can also be easily attributed to infrequent walks, smoking, lack of proper sleep and rest, emotional and mental instability, which is accompanied by the use of drugs. All these factors negatively affect the liver, gradually destroying its cells. And this often leads to disappointing forecasts and sad consequences for alcoholics and people close to them.

It is worth noting that this important internal organ is directly related to the production of sex hormones. Testosterone is also eliminated in the liver, but if it is affected by ethanol, this hormone is not processed, but is converted under the influence of alcohol into the female hormone estrogen. In addition, under the influence of alcohol, testosterone production is significantly reduced. Due to all this, there is a metabolic disorder in the body, the body ages. From about the age of fifty, a degeneration of the liver tissue occurs, stones form in the gallbladder.

Chronic alcoholics practically do not think about the harm done to the body, and do not think about any consequences. They do not care about their own health, and even more so they do not pay attention to the work of internal organs. In addition, there are no nerve endings in the liver itself and disturbances in its work are practically not noticeable. Only a few will notice some changes expressed in:

• general weakness of the body;
• apathy and complete indifference to the outside world;
• heaviness and tingling in the right side under the ribs;
• drowsiness;
• increased itching of the skin.

Often, such reactions are attributed to improper and irregular nutrition or are classified as adverse reactions to taking medications. However, the presence of these symptoms may signal an acute liver disease, the elimination of which requires all efforts to avoid unnecessary consequences. One of the widely demanded drugs that have a beneficial effect on the liver is Gepabene.

Clinical picture

What doctors say about alcoholism

Doctor of Medical Sciences, Professor Ryzhenkova S.A.:

For many years I have been studying the problem of ALCOHOLISM. It's scary when a craving for alcohol destroys a person's life, families are destroyed because of alcohol, children lose their fathers, and their husbands' wives. It is young people who often become drunkards, destroying their future and causing irreparable harm to health.

It turns out that a drinking family member can be saved, and this can be done in secret from him. Today we will talk about a new natural remedy Alcolock, which turned out to be incredibly effective, and also participates in the Healthy Nation federal program, thanks to which until July 24th.(inclusive) the remedy can be obtained FOR FREE!

Brief description of the drug

Gepabene is a complex herbal preparation that has a choleretic and hepatoprotective effect. It significantly lowers the tone of the biliary tract, normalizes the amount of bile formed, improves its qualitative composition. Thanks to this drug, damaged liver cells are restored and protected from free radicals.

The active ingredients of Gepabene are plant extracts: spotted milk thistle and medicinal fumes.

The active substance silymarin, which is contained in the extract of spotted milk thistle, is able to protect the liver from the harmful effects of acetaldehyde, which is formed during the breakdown of ethanol, and also promotes the production of proteins, which is indispensable for this organ in acute and chronic diseases.

The fumarin alkaloid contained in the extract of medicinal fumes is responsible for the normalization of the production and removal of bile from the body. The fact is that chronic alcoholism is characterized by an increase in the volume and stagnation of this substance.

Indications for the use of Gepabene are:

• diseases of the biliary tract;
• toxic alcoholic hepatitis;
• chronic liver diseases;
• fatty liver disease.

In alcohol-dependent people, fatty degeneration of the liver can often be observed, due to the passion for alcoholic beverages. Under their influence, large excesses of fats are deposited in the cells, as a result of which an inflammatory process occurs in them and, as a result, they are destroyed. This may lead to:

• oncological diseases;
• atherosclerosis;
• heart disease;
• type 2 diabetes mellitus.

With such a disease, liver function is disrupted, and subsequent alcohol consumption will lead to cirrhosis or cancer.

Gepabene is able to prevent the development of such terrible consequences, however, for this you need to completely abandon the use of alcohol, since Gepabene and alcohol are absolutely incompatible.

Contraindications to the use of this drug are acute diseases of the liver and biliary tract, hypersensitivity to the components that make up the drug, as well as children under six years of age. Gepabene should be used with caution during pregnancy and lactation. Such a reception should take place only under the supervision of a specialist.

Sometimes when taking Gepabene, the following side effects may occur:

• allergic reactions;
• increased urination;
• laxative effect.

In no case should you use ethanol-containing substances during treatment with this drug.

Gepabene for alcoholic hepatitis

In chronic alcoholism due to liver damage, more often than usual, complications occur in the form of cirrhosis and liver carcinoma. Mortality during the onset of these diseases is very high, therefore, in order to prevent this, it is necessary to take a set of measures to treat alcoholic hepatitis. For this you need:

• follow a diet;
• completely abandon alcohol;
• use hepatoprotective drugs that help restore the affected areas of the liver;
• normalize metabolic processes in the body caused by impaired liver function.

The use of Gepabene in such complex treatment contributes to a significant reduction in mortality among patients. This drug has an immunostimulating effect, which increases the antioxidant protection of liver cells. In addition, it is compatible with many other drugs, without interacting with them.

Treatment with hepatoprotective drugs is quite lengthy, and should not occur without the supervision of a specialist, since, depending on the degree of liver damage, the course of treatment can vary significantly in one direction or another. The average duration of treatment is three to six months.

The drug is released in capsules, which must be taken with meals, squeezed with a small amount of liquid. The maximum dose for an adult is 6 capsules per day.

The effect of treatment with this drug is quite high and occurs a month after the start of the medication. It normalizes all blood parameters, unlike other hepatoprotective drugs.

Gepabene has a good effect on the gallbladder. It is able to eliminate disorders in the biliary tract, so it is often used to treat gallbladder dysfunction in the elderly. In addition, it is quite well tolerated and has virtually no side effects.

Gepabene and alcohol

Is it possible to take alcohol and Gepabene at the same time. There is a clear indication in the instructions that such compatibility is not acceptable. There are several reasons for this.

Alcohol is a very strong toxin that has a destructive effect on the body. It adversely affects all internal organs, especially the intestines and liver. If it is combined with drugs, then such a relationship can cause irreparable damage to health.

Ethanol is able to increase the toxicity of drugs, and Gepabene is no exception. Although it consists of plant components, when this drug is taken with alcohol, its metabolites become quite toxic. Alcohol significantly changes metabolic processes, turning the decay products of Gepabene into dangerous substances, due to which the liver is inflicted double damage.

Alcoholic drinks destroy liver cells, and this herbal preparation has the ability to restore them. As a result, this will lead to a decrease in the therapeutic effect of taking the medicine and will reduce all the results of treatment to zero. In addition, such compatibility can significantly increase side effects and cause various complications that can lead to undesirable consequences.

Our readers write

Subject: Self cured her husband of alcoholism

From: Lyudmila S. ( [email protected])

To whom: Site administration website

This article literally pulled my husband out of the world. He's quit drinking forever and I'm pretty sure he'll never start drinking again. For the last 2 years he has been working tirelessly in the country, growing tomatoes, and I sell them in the market. Aunts are surprised how I managed to wean my husband from drinking. And he apparently feels guilty for ruining half of my life, and so he works tirelessly, almost carries me in his arms, helps around the house, in general, not a husband, but a piece of gold.

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findings

Gepabene is a herbal preparation with immunostimulating properties, choleretic and hepatoprotective effects. Its use has a very good effect on the activity of the liver, gallbladder and bile ducts. It is able to relieve pain, remove stagnant bile from the body, protect liver cells from the effects of free radicals and dangerous toxins, improve the protein-forming function of the liver, thereby contributing to the restoration of its cells. These properties have made this drug indispensable in the complex treatment of alcohol dependence that occurs with serious liver damage. Thanks to Gepabene, mortality from alcoholic hepatitis has halved. However, the simultaneous use of this medication and alcoholic beverages is strictly prohibited, since such an interaction can cause unforeseen complications, significantly increase the load on the liver, completely minimizing all the results of treatment. In addition, alcohol is able to change the process of biotransformation of this drug, turning its metabolites into poisons that have a destructive effect on this important internal organ. Thus, it is better to treat Gepabene under the supervision of the attending physician, fully following all his instructions. And refuse to use strong drinks for the duration of the course of treatment with hepatoprotectors.

Drawing conclusions

If you are reading these lines, we can conclude that you or your loved ones are somehow suffering from alcoholism.

We conducted an investigation, studied a bunch of materials and, most importantly, tested most of the methods and remedies for alcoholism. The verdict is:

All drugs, if they gave, then only a temporary result, as soon as the reception was stopped, the craving for alcohol increased sharply.

The only drug that has given a significant result is Alcolock.

The main advantage of this drug is that it once and for all removes cravings for alcohol without a hangover. In addition, he colorless and odorless, i.e. to cure a patient of alcoholism, it is enough to add a couple of drops of medicine to tea or any other drink or food.

In addition, now there is a promotion, every resident of the Russian Federation and the CIS can get Alcolock - FOR FREE!

Attention! Cases of sale of counterfeit drug Alcolock have become more frequent.
By placing an order using the links above, you are guaranteed to receive a quality product from the official manufacturer. In addition, when ordering on the official website, you receive a money back guarantee (including transportation costs) if the drug does not have a therapeutic effect.

Which drug should be used to treat liver diseases: "Gepabene" or "Essentiale"? In any case, the choice of a drug should be left to the attending physician, who, having studied the results of a diagnostic examination, determines the appropriateness of using a particular medication. "Gepabene" is a combined remedy of plant origin, the action of which is aimed at normalizing the functioning of the liver in various ailments. You need to take the medication after reading its instructions.

Release form and composition

Gepabene is produced in the form of capsules, which have a light brown color and a hard gelatinous structure. Inside each capsule is a powdery consistency with an orange-brown tint. Tablets are placed in blisters of 10 pieces, in packs there are 3 or 10 blisters. The components of the medication are:

• extract of grass wild rue;
• milk thistle extract;
• magnesium salt of stearic acid;
• ethylene glycol polymer;
• corn starch;
• gelatin;
• food additive E172;
• distilled water;
• food additive E171.

Mechanism of action

The pharmaceutical preparation, due to its combined composition, has the ability to stop the convulsive contraction of the gallbladder and its ducts, thereby allowing bile to enter the intestine more easily. Entering the body, the constituent drugs normalize the amount of secretion. The active formula exhibits an antitoxic effect, which is important in cases of intoxication. The main advantage of "Gepabene" is its ability to form new liver cells and cope with various kinds of pathological processes in this organ. The medicine, entering the digestive organ, mixes with bile and begins to break down in the intestines and liver.

Indications

Plant extracts in the composition of the drug have a hepatoprotective effect in acute and chronic intoxications.

It is recommended to use "Gepabene" as part of the complex treatment and prevention of various ailments of the biliary tract and liver diseases. The components in the composition of the described medication allow you to treat such pathological conditions in the human body:

• impaired motility of the biliary tract;
• inflammation of the digestive gland responsible for the production of bile, occurring in the chronic stage;
• liver disease, characterized by the death of liver tissue;
• fatty liver.

How to take "Gepabene" in the treatment of the liver?

It is necessary to use the pharmaceutical agent "Gepabene" strictly according to the instructions and after consulting with a specialized doctor. The medicine is taken orally during meals, 1 capsule three times a day. The pill is swallowed whole, without biting, washed down with a sufficient volume of purified water. When the patient is worried about severe pain, doctors are allowed to drink 1 more capsule at bedtime. The dosage calculated per day should not exceed 6 pills, divided into 3-4 doses per day.

Can it be used during pregnancy and lactation?

It is allowed to use the drug "Gepabene" for women in the position for the liver in extreme cases and only as directed by a specialized doctor. Gepabene is also taken with caution during the lactation period, since the components of the medicine are able to penetrate into breast milk. Dosage for pregnant and lactating women is selected individually.

Contraindications

The drug is not recommended for use in children under 6 years of age, as well as in case of hypersensitivity to the components of the drug. Contraindications are acute forms of liver diseases and diseases of the bile ducts, through which bile is transported. The instructions for Gepabene indicate that for its use in aged patients and children, dose adjustment is not required and the intake occurs according to the general scheme. When using "Gepabene" it is contraindicated to drink alcoholic beverages. In the process of treatment, it is extremely important to follow a therapeutic diet.

Overdose

The drug is taken after consulting a doctor.

To date, no cases of overdose with the described pharmaceutical agent have been identified. However, if it occurs, you should immediately contact a medical institution for qualified medical help. To prevent an overdose, the medicine must be taken strictly according to the scheme prescribed by the attending physician.

Side effects

Usually "Gepabene" is well tolerated by patients and does not show serious side symptoms. It is extremely rare that, due to its diuretic action, the medication provokes frequent loose stools. In the process of using this medicine for the treatment of ailments of the liver or biliary tract, an increased level of urine production, as well as allergic reactions, may be observed.

Drug analogues

If for some reason it is not possible to take "Gepabene", the patient may be prescribed his analog drugs. According to the active substance, the drug has no synonyms, as it is made on the basis of plant components, which provide it with a unique composition. According to the pharmacological group, the analogues of "Gepabene" are:

• "Ursosan";
• "Karsil";
• "Heptral";
• "Vitanorm";
• "Hepatosan";
• "Antraliv";
• "Essliver";
• "Hepa Merz";
• "Silymarin";
• "Thiolipon";
• "Heptor";
• "Legalon";
• "Octolipen";
• "Geptrong";
• "Erbisol";
• "Molixan";
• "Silimar";
• "Glutargin";
• "Cavehol";
• "Tykveol";
• "Ursodez";
• "Octolipen";
• "Hepabos";
• "Maxar";
• "Thiotriazolin";
• "Milif";
• "Ornitsetol";
• "Silegon";
• "Choludexan";
• "Urdoksa";
• "Metrop";
• "Sirepar";
• "Ursofalk";
• Livedox;
• "Choludexan";
• "Essentiale N";
• "Rezalut Pro";
• "Ursor";
• "Methionine";
• "Phosfonciale";
• "Ornitsetil";
• "Lipoid";
• "Essentiale forte N".

The drug improves the functional state of liver cells.

It should be borne in mind that each drug has its own instructions for use, contraindications and features of use. Therefore, they use the analogue of "Gepobene" only after consulting with the attending doctor, who will assess the patient's condition and prescribe the necessary therapeutic regimen. Otherwise, the risk of side symptoms and complications of the course of the disease increases.

The site provides reference information for informational purposes only. Diagnosis and treatment of diseases should be carried out under the supervision of a specialist. All drugs have contraindications. Expert advice is required!

Gepabene drug

Gepabene- a drug from the series hepatoprotectors vegetable origin. Hepatoprotectors - substances for the treatment and protection of the liver. The active components of Gepabene are the alkaloids fumarin, which is included in the extract of fumes officinalis, and silymarin, which is included in the extract of milk thistle fruits.

When liver cells are damaged, the integrity of their membranes is violated, the cell structures responsible for the production of the main part of energy are affected. Communications between hepatocytes are broken. As a result, metabolism suffers, bile secretion decreases, liver cells lose their ability to recover.

The active substances of the drug Gepabene, being in an optimally balanced ratio, affect all these processes, restoring the functioning of the liver.
Fumarin properties:

• has a choleretic effect;
• reduces the tone of the biliary tract and the sphincter of Oddi;
• regulates the composition of bile and the formation of its quantity;
• normalizes the motor function of the gallbladder and ducts.

As a result of exposure to fumarin, bile enters the intestine more freely, which prevents its stagnation and the formation of stones in the gallbladder and biliary tract.

Silymarin properties:

• Stabilizes membranes;
• restores liver cells;
• has an antioxidant effect;
• improves the protein-forming function of the liver in acute and chronic diseases.

The maximum concentration of the drug in the blood is reached 2 hours after administration. The half-life is about six hours.

Forms of release and composition

The drug is produced in capsules packed in blisters of 10 pieces. In a cardboard box - 3 blisters.

Each capsule contains 275.1 mg of medicinal fume dry extract, 83.1 mg of milk thistle fruit dry extract and excipients.

Instructions for use Gepabene

Indications for use

Hepabene is used:

• in the complex therapy of biliary dyskinesia;
• with chronic intoxication processes in the liver;
• with hepatitis having a chronic course;
• with fatty degeneration of the liver.

Also, the drug is prescribed after surgery to remove the gallbladder.

Contraindications

The drug is contraindicated in case of hypersensitivity of the body to its components, in acute inflammatory processes in the liver and biliary system, as well as in children under the age of 18 years.

Side effects

When using Gepabene, side effects are minimal. Allergic manifestations are possible. In some cases, there may be a loosening of the stool and an increase in the amount of urine excreted.

Gepabene treatment

How to take Gepabene?
The Gepabene capsule is taken entirely orally during meals, washed down with water. When treating with this drug, it is necessary to strictly observe the regimen and diet prescribed by the attending physician in accordance with the existing disease.

Alcohol in the treatment of Gepabene is not recommended.

Dosage
The usual dosage of the drug is 1 capsule 3 times a day. If the patient is concerned about night pains in the liver area, then 1 additional capsule is prescribed for the night. The maximum dosage is 2 capsules 3 times a day.

To date, no cases of drug overdose have been described. If the maximum daily dose is exceeded, you should consult a doctor.

Gepabene for children

Children under the age of 18 are not prescribed Gepabene.

Use during pregnancy and lactation

For women during pregnancy and lactation, the appointment of the drug is possible only by the attending physician, on an individual basis, if absolutely necessary.

No adverse effects of Gepabene on the fetus have been identified.

drug interaction

The interaction of Gepabene with other drugs has not been described.

Karsil or Gepabene?

Both Karsil and Gepabene are hepatoprotectors. Both drugs are well tolerated. Gepabene differs from Karsil in the presence in its composition of the extract of fume medicinal - its action is more effective. Therefore, in case of insufficient effect from taking Karsil, it is better to stop your choice on Gepabene. In case of individual intolerance to Gepabene, you can try taking Karsil.

Since hepatoprotectors are usually prescribed for long courses, a treatment regimen using both drugs is often used: 2 months - Gepabene, 2 months - Karsil, etc.

Gepabene's analogs

Hepatoprotective drugs, i.e. analogues of Gepabene are:

• LIV-52;
• Sirepar;
• Gepadif;
• Silimar;
• Sibektan;
• Essentiale forte;
• Essliver forte;
• Karsil;
• Metaprot;
• lipoic acid;
• ursodeoxycholic acid.

But they differ from Gepabene in their composition. There is not a single synonym for Gepabene (structural analogue).

When choosing a drug to protect and treat the liver, you should consult a doctor.

Gepabene belongs to the category of phytopreparations with a pronounced hepatoprotective effect. The high therapeutic effect of the drug is due to the content in its composition of extracts that have a powerful effect on the liver. The drug stimulates protein synthesis, affects metabolic processes, increases the ability of cells to regenerate and removes toxic compounds from the body.

In the presence of spasms of the gallbladder, the medication alleviates the patient's condition and stops the attacks. You can take a herbal remedy at the risk of functional abnormalities of the liver, as part of complex therapy, or to prevent recurrence of manifestations of chronic pathologies.

1. Instructions for use

The dosage regimen and contraindications to the herbal remedy are contained in the instructions. Separate paragraphs contain information about possible side symptoms, special instructions, the nuances of drug interactions and the consequences of an overdose. Additionally, the manufacturer describes the composition of the hepatoprotective agent and explains the mechanism of its effect on the body. The instructions provide a standard dosing regimen, but in some pathologies, the dosage regimen of the herbal remedy can be changed by the doctor.

pharmachologic effect

Gepabene has a pronounced choleretic effect, reduces hyperkinesia of the bile ducts and the sphincter of Oddi, which acts as a regulator of the flow of pancreatic and bile secretions into the 12th finger. gut.

The drug prevents the reverse ejection of the contents from the intestine into the pancreatic and biliary tract, thereby normalizing the outflow of bile entering the intestine. The active components of the drug have a balanced ratio and have the following effect on the liver.

Fumarin:

Silymarin:

• It has a restorative effect on liver cells;
• Has antioxidant properties;
• Stabilizes membranes;
• Increases the formation of protein in the liver during acute and chronic diseases.

Thanks to fumarin, bile passes freely into the intestines, without creating congestion that causes the formation of stones in the biliary and biliary tract. Silymarin binds free radicals and toxins, has a restorative and membrane-stimulating effect on hepatocytes. With physiological need (acute inflammation) it is able to activate the production of proteins by liver cells.

The peak concentration of active substances is reached 2 hours after ingestion. Their half-life is 5-6 hours. The flavonoids that enter the body, which are part of silymarin, are excreted mainly in bile and are subject to hepato-intestinal recirculation. Silymarin is almost insoluble in water, and its metabolites are excreted in the bile.

Indications for use

Gepabene is indicated for admission in the following cases:

Mode of application

Gepabene take 1 caps. three times a day. In the presence of a pain syndrome that occurs at night, before going to bed, take another capsule, which is swallowed whole, without violating integrity, and washed down with water. The maximum possible daily dose of the drug is 6 capsules, which are drunk in 3-4 doses. The standard course of treatment is 3 or more months.

During treatment, the patient must strictly adhere to the dosage prescribed by the doctor and follow the recommended diet and regimen. During the entire course of administration, the use of ethanol is prohibited.

Release form, composition

Gepabene is produced in the form of capsules in blisters of 10 pieces, packed in cardboard boxes containing 3 blisters.

Each capsule contains:

• Active substances (mg) - dry extract of Dymyanka (275.1), dried extract of the fruit of Milk Thistle (83.1);
• Auxiliary components - colloidal silicon dioxide, titanium dioxide, magnesium stearate, iron oxide (red, yellow, black), copovidone, talc, macrogol, gelatin, cellulose, corn starch.

Interaction with other drugs

The interaction of Gepabene with alcohol and other drugs is as follows:

• Simultaneous use of drugs containing silymarin, oral contraceptives, or drugs used in estrogen replacement treatment reduces the effectiveness of the latter;
• Stimulates the inhibition of the cytochrome P450 system, thereby enhancing the effect of Vinblastine, Diazepam, Alprazolam, Lovastatin, Ketoconazole;
• It is forbidden to take Gepabene and alcohol together.

2. Side effects

After taking Gepabene, there is a possibility of the following side effects:

• Allergic reaction in the form of skin rashes, itching, difficulty breathing;
• In the digestive tract: nausea and rarely diarrhea;
• Increased diuresis of urine.

Overdose

Episodes of severe conditions, provoked by an overdose of herbal medicine, have not been recorded in medical practice. The composition of Gepabene includes plant extracts with pronounced therapeutic properties, which, if ingested excessively, can cause an allergic reaction. Additionally, in the list of side effects in case of an overdose, the manufacturer notes diuresis and a laxative effect.

Contraindications

Gepabene is contraindicated in the following cases:

• With hypersensitivity to the components of the drug;
• With acute inflammation of the liver and biliary tract;
• Under the age of 18.

During pregnancy

There is no information on the negative effect of Gepabene on the pregnant woman and the fetus. But during pregnancy and lactation, the medicine is used with special precautions and under the supervision of a physician.

There is no clinical experience of studies on the effect of the drug on the body of children.

3. Special instructions

Influence on the ability to drive vehicles and control mechanisms

Gepabene does not affect the central nervous system. Taking a herbal medicine cannot provoke a decrease in psychomotor reactions and a violation of concentration.

Pregnancy and lactation

The list of absolute contraindications does not include pregnancy and breastfeeding. The manufacturer does not limit the use of herbal medicine, but recommends that you first consult with your doctor.

Extracts from the composition of the drug can provoke allergic reactions in a pregnant woman (in most cases, Gepabene is replaced by other medicines). During the lactation period, you should not combine treatment with breastfeeding. Herbal substances can cause digestive or immune adverse reactions in a newborn baby.

Application in childhood

Phytopreparation is not used in pediatrics.

For impaired renal function

Kidney dysfunctions are not included in the list of contraindications, but in case of inflammatory pathologies, it is recommended to take the herbal remedy after consulting a doctor.

Gepabene is a modern drug from the group of hepatoprotectors. It is of vegetable origin. The substances contained in it are able to heal and protect the liver. Among the active components of the drug, the alkaloid fumalin from the extract of fumigation and silymarin from the extract of milk thistle fruit. How does the medication work?

Gepabene properties

The liver begins to suffer at the stage of the destructive effect on the cells. The process begins with a violation of the integrity of the membrane layer, damage to the cell structures that are responsible for generating most of the energy. In this case, the connection between hepatocytes is gradually broken. Metabolism at the cellular level suffers, and bile secretion is disturbed. As a result, the cells of the body simply lose their ability to recover.

The balance of the active components of Gepabene allows you to influence each of these pathological processes, which leads to the restoration of liver functions. Let's analyze the effect of active substances on the liver using the table.

Fumarin helps bile to freely enter the intestines, so it does not stagnate. This serves to prevent gallstones. But silymarin is responsible for the restoration of liver cells, and also increases their functionality. 2 hours after taking the drug in the blood, its maximum concentration is reached, but the half-life lasts about 6 hours.

Gepabene preparation: instruction

The drug is produced in capsules, which are packed in blisters (10 pieces each). At the same time, in one carton package there are three such blisters. One capsule contains the following substances:

• Dry extract of medicinal fumes - 275.1 mg;
• Milk thistle fruit extract - 83.1 mg;
• Auxiliary components.

Indications for use of Gepabene

The drug is taken as prescribed by the attending physician. Self-medication can be hazardous to health. Liver diseases at first proceed unnoticed, so the risk of detecting such an ailment at a late stage is very high. At the slightest suspicion, you should seek medical help. Gepabene is indicated by specialists in such cases:

• Chronic intoxication of the liver;
• As part of the complex therapy of biliary dyskinesia;
• With chronic hepatitis;
• With cirrhosis of the liver;
• With fatty degeneration of the liver;
• After surgical removal of the gallbladder.

Contraindications

Despite the plant origin of the drug, there are some contraindications. For this reason, the use of such a remedy as Gepabene should be started in accordance with the doctor's prescriptions. It is contraindicated in such cases:

• Hypersensitivity to the components of the drug;
• The presence of an acute inflammatory process in the liver, biliary system;
• The patient's age is up to 18 years.

Side effects of Gepabene

Studies and use of the drug in the treatment of liver ailments prove that side effects are minimal. Rarely, allergic manifestations occur. It is also possible to loosen the patient's stool or increase the amount of urine excreted.

Mode of application

The capsule should be taken with meals. It must be taken with water. Gepabene treatment will have the desired effect if the patient follows the diet and regimen prescribed by the doctor. They differ somewhat depending on which disease is being treated.

Important: Alcohol should not be taken during this therapy.

Dosage

Usually the drug is taken three times a day, one capsule. In cases where the patient is disturbed by pain at night, one additional capsule is prescribed, which is taken at bedtime. In the most difficult situations, the doctor recommends the maximum dosage: two capsules three times a day. Children under 18 years of age are not prescribed Gepabene.

Use during pregnancy and breastfeeding

If absolutely necessary, even during these special periods, the treatment of Gepabene is allowed. Therapy is carried out under the supervision of the attending physician on an individual basis. To date, there have been no negative interactions on the fetus while taking this medication.

Analogues

In addition to Gepabene, there are other hepatoprotective drugs. They differ in composition, but have a similar spectrum of action. The appropriate treatment will be selected by the attending physician, who will be familiar with the features of the clinical case. Analogues include:

• Karsil;
• Sirepar;
• Essentiale forte;
• LIV-52;
• Silimar;
• Gepadif;
• Essliver forte;
• Heptral;
• Metaprot;
• Ursodeoxygolic acid;
• Lipoic acid.

The interaction of Gepabene with other drugs has not been sufficiently studied at the moment. The shelf life of the drug is 5 years. Store it at temperatures up to 25 degrees out of the reach of children. Some patients complain of a strong laxative effect of the drug on the body. In this case, along with taking Gepabene, the patient was prescribed a special diet containing rice and other foods that promote constipation. For additional advice, you can contact the specialists of our website right now, but you should not take any means for treating the liver without the recommendation of your doctor.